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DE102018131131A1 Continuous process to obtain a crystalline monosaccharide  
The invention relates to a continuous process for obtaining a crystalline monosaccharide, comprising a continuous crystallization of the monosaccharide in a main crystallizer (10), wherein in the...
DE202011111124U1 Polymorph of a tretrasaccharide containing N-acetyllactosamine  
A polymorph of Galpβ1-4GlcNAcpβ1-3Galpβl-4Glc (LNnT), characterized in that it has X-ray powder diffraction reflections based on a measurement using CuKa radiation, at a 2Θ angle of 20.32 ± 0.20,...
DE202013012839U1 New polymorphs from LNnT  
A crystalline LNnT polymorph IV, characterized in that it shows X-ray powder diffraction reflections based on a measurement using CuKa radiation at 2Θ angles of 8.16 and 15.41, more preferably at...
DE202017007249U1 Separation of oligosaccharides from the fermentation broth  
A solid sialylated oligosaccharide, the solid sialylated oligosaccharide being a spray dried or crystalline acidic human milk oligosaccharide selected from 6'-sialylylactose (6'-SL),...
DE202017007248U1 Separation of oligosaccharides from the fermentation broth  
A neutral human milk oligosaccharide containing N-acetylglucosamine, selected from LNT, LNnT or lacto-N-triose II, obtained by a process for separating a neutral oligosaccharide containing...
DE102018007478A1 Medicinal or nutritional supplements for the treatment and / or prophylaxis of joint diseases and / or inflammatory joint diseases  
Pharmaceutical or food supplements for the treatment and / or prophylaxis of diseases of the joints, especially arthrosis, which contain a collagen hydrolyzate in combination with free...
DE202013012829U1 Improving the stability and purity and increasing the bioavailability of human milk oligosaccharides or precursors or mixtures thereof  
A spray-dried oligosaccharide from human milk (HMO) or a spray-dried HMO mixture with improved stability after prolonged storage at temperatures above 25 ° C and produced by a process comprising...
DE202013012827U1 Improving the stability and purity and increasing the bioavailability of human milk oligosaccharides or precursors or mixtures thereof  
Spray-dried neutral oligosaccharide from human milk (HMO) or a spray-dried neutral HMO mixture with improved stability after prolonged storage at temperatures above 25 ° C., which is produced by a...
DE202014011399U1 Neutral human milk oligosaccharides (HMOs) from microbial fermentation  
A concentrate of a neutral human milk oligosaccharide (HMO) product containing a desired HMO in a concentration of ≥ 100 g / l and one or more impurities in an aqueous solution, the HMO product...
DE202015009782U1 Separation of 2'-O-fucosyllactose from fermentation broth  
Crystallized 2-O'-fucusyllactose (2'-FL) made by a process comprising the steps of: i. Culturing a genetically modified cell with a recombinant gene coding for a 1,2-fucosyltransferase and capable...
DE202015009775U1 Separation of 2'-FL from a fermentation broth  
Crystallized 2-O'-fucusyllactose (2'-FL) produced by a process comprising the following steps: i. Culturing a genetically modified cell containing a recombinant gene coding for a...
DE102018116200A1 METHOD FOR PRODUCING A NUCLEOTIDE SUGAR  
In a process for producing a monosaccharide-1-nucleoside diphosphate, a monosaccharide, a monosaccharide-1-phosphate kinase, a nucleoside triphosphate sugar-1-phosphate nucleosidyl transferase, a...
DE102010034968B4 Polymerizable compounds and liquid-crystal media  
Liquid-crystalline medium which comprises one or more compounds selected from the compounds of the formulas IA-1 to IA-10contains wherein R1' to R5' each independently of one another hydrogen,...
DE102018201920A1 Liquid functionally improved isomalt  
The present invention relates to a liquid isomalt composition comprising 6-O-alpha-D-glucopyranosyl-D-sorbitol (1,6-GPS) and 1-O-alpha-D-glucopyranosyl-D-mannitol (1,1-GPM ) and the other...
DE102018201916A1 Solid functionally improved isomalt  
The present invention relates to a solid isomalt composition comprising 6-O-alpha-D-glucopyranosyl-D-sorbitol (1,6-GPS) and 1-O-alpha-D-glucopyranosyl-D-mannitol (1,1-GPM ) and the other...
DE102017010898A1 New inhibitors of shikimic acid pathway  
The present invention relates to novel inhibitors of the shikimic acid pathway (shikimate route), to pharmaceutical compositions containing these novel inhibitors, to processes for the preparation...
DE102017125888A1 New engineered T cell receptors and their use in immunotherapy  
The present invention relates to antigen-recognizing constructs against COL6A3 antigens. In particular, the invention provides novel engineered T cell receptor (TCR) based molecules which are...
DE102015219343B4 A method of processing seaweed-derived galactose using agarase  
Process for preparing galactose, the process comprising: treating a residue of red algae by steps, comprising saccharification of the red algae by hydrolysis with an acid and filtration of the red...
DE112017002818T5 Compound for use in an enzymatic reaction and mass spectrometry methods  
A compound used in the conventional enzymatic reactions and mass spectrometry methods must be changed in structure as a substrate compound, such as the length of an alkyl chain contained therein,...
DE102015214603B4 Phosphorus containing aminoglycoside salts  
Compound of Formula 1 wherein the aminoglycoside is selected from the group of aminoglycoside or aminoglycoside group-containing antibiotics, where y is selected from 0.1 to 20, where n is...
DE102017115966A1 Polypeptide molecule with improved dual specificity  
The present invention relates to a bispecific polypeptide molecule, comprising a first polypeptide chain and a second polypeptide chain, which provide a binding region, derived from a T cell...
DE112016005245T5 METHOD FOR THE FRACTIONATION OF LIGNOCELLULOSE-CONTAINING BIOMASS  
This invention aims to develop a process for fractionating lignocellulosic biomass by contacting lignocellulosic biomass with treating liquid in a closed system at a temperature not exceeding 200...
DE102017003004A1 Cationic polymers with D-fructose substituents  
The invention relates to novel cationic polymers which are D-fructose conjugated, whereby they are able to interact selectively with specific structural elements on cell surfaces. The task was to...
DE102017002810A1 Sialic acid derivatives with CC triple bond and their preparation  
Sialic acid derivatives containing a CC triple bond are described, processes for their preparation, conjugates prepared therefrom and pharmaceutical compositions containing them.
DE102017002252A1 Enzymatic process for the production of fructose  
The present invention relates to a process for the preparation of aqueous solutions of D-fructose from a di-, oligo- or polysaccharide. Current methods are based on the generation of D-glucose...
DE102007032799B4 Sugary metal complexes and their use  
Sugar-containing metal complexes of substituted polypyridines of general formula I.(L1n)(L2m)(L3O)(L4p)(L5q)M+/-.consisting of ligands L1 to L5, wherein at least one of these ligands L1 to L5 is a...
DE102006035020B4 Stabilization of NAD / NADH  
A test element for the determination of an analyte comprising (i) a coenzyme dependent enzyme or a substrate for such an enzyme and (ii) as a coenzyme a compound having the following general...
DE202015009594U1 New dimers of cytidine derivatives  
A cytidine derivative dimer having the following general formula (I), wherein: R 1 is a CC alkyl, CC-substituted alkyl, - (CH) -Ph or substituted - (CH) -Ph; in - (CH) -Ph, n = 0, 1, 2, 3 ~ 10 and...
DE102016225419A1 Olfactory signaling after overheating in technical facilities by pyrolysis of fragrance derivatives  
The present invention relates to a method for providing a technical device with a warning signal against heating and a kit with which the method can be carried out.
DE10113265B4 Use of a stabilized nucleic acid for the production of a protein  
The invention teaches the use of a linear nucleic acid stabilized against exonuclease degradation in a method of producing a protein encoded by a base sequence of the nucleic acid in a cell-free...
DE102016116121A1 Process for the epimerization of saccharides  
The invention relates to a process for the epimerization of saccharides by heating a saccharide dissolved in a solvent in the presence of a metal-containing catalyst, an aldose being contacted...
DE102016124844B3 DNA probes for in situ hybridization of chromosomes  
Kit, probe mixtures and probes for the detection of a chromosome aberration. A gene probe obtained by a method comprising the following steps: (a) examining genomic sections for sequence regions...
DE102011118022B4 Antibodies against the prostate-specific stem cell antigen and its use  
The invention relates to recombinant antibodies that bind to prostate-specific stem cell antigen (PSCA). The antibody according to the invention contains complementarity-determining regions (CDR)...
DE102007063902B3 Aptamers that bind to a target molecule involved in hemostasis  
Aptamer that binds to a target molecule involved in hemostasis, the aptamer being an aptamer that binds to activated protein C, the aptamer having a dissociation constant KD binds to activated...
DE102011018627B4 Modified nucleotides  
Connection with structure (I): or a salt, a conjugate base, a tautomer or a dissociated form thereof, wherein P1 is a phosphate group; P2 is a phosphate group; Nus is a nucleoside structural unit...
DE112012003416B4 Process for the preparation of 2- (4-methoxycarbonylpyrazol-1-yl) adenosine and 2- (4-ethoxycarbonylpyrazol-1-yl) adenosine  
A process for the preparation of 2- (4-methoxycarbonylpyrazol-1-yl) adenosine of the formula Ia and 2- (4-ethoxycarbonylpyrazol-1-yl) adenosine of the formula Ib by reaction of...
DE102015009439B4 Triple target HIV-1 NAT for the detection of all known genotypes  
A primer / sample set for the detection of HIV, in particular HIV-1, comprising at least one primer / sample set 1 consisting of oligonucleotides comprising SEQ ID NOs 1, 2 and 3; Primer / sample...
DE102006012414B4 Chemical process for the production of degraded polygalactomannans  
A process for recovering degraded polygalactomannan comprising the steps of: providing a suspension of a polygalactomannan in an aqueous alcoholic solution having an alcohol concentration between...
DE202017002052U1 Nucleoside pearl necklaces sequencing  
An apparatus for DNA sequencing by passing a single-stranded DNA or RNA strand with anhybridized, chemically modified (nucleo-) bases, nucleosides or nucleotides by a biological or non-biological...
DE102015219651A1 Compositions containing sugar amine and fatty acid  
Compositions are described containing a) one or more sugar amines of the formula (I) wherein R1 and R2 are independently H, CH3 or 2-hydroxyethyl and / or one or more corresponding protonated...
DE102007041476B4 Aptamers that bind to a target molecule involved in hemostasis  
Aptamer that binds to a target molecule involved in hemostasis, the aptamer being a thrombin-binding fusion aptamer, comprising at least two thrombin-binding aptamers and at least one linker, the...
DE202008018643U1 Nucleoside phosphoramidate drugs  
Compound according to the following formula: in which (a) R1 Is hydrogen, methyl, ethyl, n-propyl, i-propyl or a substituted or unsubstituted phenyl, the substituent of the substituted phenyl...
DE102015011780A1 New glutaminylcyclase inhibitors  
The invention relates to a compound of the formula (I) for use as a glutaminylcyclase inhibitor, to a composition containing the compound for use as a QC inhibitor and to processes for the...
DE102015214603A1 Phosphorus-containing aminoglycoside salts  
The object is to provide aminoglycoside compounds which ensure a sustained release of aminoglycoside over clinically relevant periods in therapeutically effective concentrations. Aminoglycoside...
DE112012003470B4 Process for the preparation of 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosine monohydrate  
Process for the preparation of 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosine monohydrate of the formula I. comprising the steps: a) Allowing 2- (4-methoxycarbonylpyrazol-1-yl)...
DE102015219343A1 A process for preparing galactose derived from marine algae using agarase  
A method for preparing galactose by means of an enzymatic treatment of a red algal residue is provided. The process for preparing galactose comprises: preparing a residue; Treating the residue...
DE102015008536A1 Discontinuous oligonucleotide ligands  
The present invention relates to an oligonucleotide conjugate K of the structure or a pharmaceutically active salt thereof, wherein RNA1, RNA2, RNA3 and RNA4 are each strands of a ribonucleic acid...
DE19549875B4 Use of magnetic particles to isolate nucleic acids  
Magnetic particles with an outer glass surface that is essentially pore-free or has pores with a diameter of less than 10 nm and ferromagnetic particles with a glass surface can preferably be used...
DE112015001085T5 Antibodies, uses and procedures  
The present invention relates to anti-human OX40L antibodies, new medical uses and methods.
DE102015216558A1 PROCEDURE AND TEST KIT FOR FAST ISOLATION OF NUCLEIC ACIDS BY SMOKE SURFACES  
The invention relates to a method for isolating nucleic acids from nucleic acid-containing samples, characterized in that free nucleic acids released by lysis are bound to a solid phase with a...

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